| Name | Title | Business Phone | ||
|---|---|---|---|---|
|
|
Christiaan Leeuwenburgh | Professor Department Of Physiology And Aging | (352) 273-5735 | cleeuwen@ufl.edu |
|
|
Karyn Esser | Professor And Chair | (352) 273-5728 | kaesser@ufl.edu |
|
|
Thomas C Foster | Professor, Evelyn F. McKnight Chair For Research On Cognitive Aging And Memory | (352) 273-0033 | foster1@ufl.edu |
|
|
Shinichi Someya | Associate Professor | (352) 294-5167 | someya@ufl.edu |
|
|
Rui Xiao | Associate Professor | (352) 273-9389 | rxiao@ufl.edu |
Core leader: Dr. Christiaan Leeuwenburgh
Our Mission
The UF Older Americans Independence Center’s Metabolism and Translational Science Core provides the infrastructure, laboratory space, trained personnel, consultative and collaborative scientific expertise to investigate aspects of the biology of aging and metabolism. A wide spectrum of established methodologies of biochemistry and molecular biology and selected measures of metabolism address a set of genetic and biological themes focused on biological mechanisms underlying aging in general, and sarcopenia and disability in particular.
Biomarkers of Aging & Disease
- Inflammation
- Senescence
- Cardiovascular Disease
- Oxidative stress
- Autophagy
Mitochondria in Aging & Disease
- Oxidative and glycolytic energy metabolism
- Electron transport system function
- Real-time cell metabolic analysis
- Fuel utilization preference
- Mitochondrial biogenesis & transcriptional activity
- MtDNA mutations and damage
- Mitophagy
Major Equipment
- Luminex 200
- Jess System
- Bio-Tek Synergy HTX Multi-Mode Microplate Reader
- Oxygraph-2k (Oroboros)
- Agilent/Seahorse XFe96 Flux Analyzer
Sample types (depending on the analysis)
- Plasma, Serum, Tissues, Tissue Homogenates, Cells, Mitochondria
For more details about the Core, its services, fees, and consultation, contact:
Brian Bouverat, MS, Research Manager, (Biomarkers of Aging & Disease)
Stephanie Wohlgemuth, Ph.D., Staff Scientist, (Mitochondria in Aging & Disease)