Rui Xiao

Rui Xiao, Ph.D.

Associate Professor

Department: MD-BIOLOGY OF AGING
Business Phone: (352) 273-9389
Business Email: rxiao@ufl.edu

About Rui Xiao

Additional Positions:
Member
2018 – Current · Institute on Aging Executive Board
Affiliated Member
2016 – Current · Center for Smell and Taste
Affiliated Member
2016 – Current · UF Health Cancer Center
Affiliated Member
2015 – Current · UF Genetics Institute
Member
2015 – Current · Institute on Aging
Member
2022 – 2025 · College of Medicine Graduate Program in Biomedical Sciences Admissions Committee
Member
2022 – 2024 · College of Medicine Scientific Review Committee

Accomplishments

Exemplary Teacher Award
2022 · College of Medicine, University of Florida
Exemplary Teacher Award
2021 · College of Medicine, University of Florida
Research Scholar
2018-2021 · American Cancer Society
Exemplary Teacher Award
2018 · College of Medicine, University of Florida
Pepper Scholar
2015-2017 · University of Florida Claude D. Pepper Older Americans Independence Center (OAIC)
AHA Postdoctoral Fellowship
2011-2013 · the American Heart Association
Outstanding Academic Achievement Award
2008 · Biophysics Program, the Ohio State University
National Institute of Neurological Disorders and Stroke (NINDS) Scholarship Winner
2007 · Keystone Symposium
Outstanding Academic Achievement Award
2006 · Biophysics Program, the Ohio State University

Teaching Profile

Courses Taught
2017-2023
GMS6487 Anti-aging Interventions
2018-2023
GMS6099 Research Methods in Gerontology
2017-2019,2021
GMS6070 Sensory and Motor Systems
2018
GMS7980 Research for Doctoral Dissertation
2016
GMS6893 Clinical and Translational Science Seminar Series
2021
GMS6622 Mitochondrial Biology in Aging and Disease

Research Profile

Areas of Interest
  • Aging
  • C. elegans
  • Molecular genetics
  • Sensory biology
Open Researcher and Contributor ID (ORCID)

0000-0001-5541-6685

Publications

2023
The role of mitochondria in the recovery of neurons after injury.
Neural regeneration research. 18(2):317-318 [DOI] 10.4103/1673-5374.343907. [PMID] 35900413.
2021
A novel role of the mitochondrial iron-sulfur cluster assembly protein ISCU-1/ISCU in longevity and stress response
GeroScience. 43(2):691-707 [DOI] 10.1007/s11357-021-00327-z. [PMID] 33527323.
2021
Comparative toxicities of BPA, BPS, BPF, and TMBPF in the nematode Caenorhabditis elegans and mammalian fibroblast cells.
Toxicology. [DOI] 10.1016/j.tox.2021.152924.
2021
Distinct temporal actions of different types of unfolded protein responses during aging
Journal of Cellular Physiology. 236(7):5069-5079 [DOI] 10.1002/jcp.30215. [PMID] 33345326.
2021
Fungal Epithiodiketopiperazines Carrying α,β-Polysulfide Bridges from Penicillium steckii YE, and Their Chemical Interconversion.
Chembiochem : a European journal of chemical biology. 22(2):416-422 [DOI] 10.1002/cbic.202000403. [PMID] 32816319.
2021
Iron homeostasis and organismal aging.
Ageing research reviews. 72 [DOI] 10.1016/j.arr.2021.101510. [PMID] 34767974.
2021
The role of neurosensory systems in the modulation of aging
Handbook of the Biology of Aging. 285-295 [DOI] 10.1016/b978-0-12-815962-0.00013-5.
2021
TRP channels: Intestinal bloating TRiPs up pathogen avoidance.
Cell calcium. 98 [DOI] 10.1016/j.ceca.2021.102446. [PMID] 34303264.
2020
Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults
Cells. 9(12) [DOI] 10.3390/cells9122579. [PMID] 33276460.
2020
BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome.
Brain structure & function. 225(6):1743-1760 [DOI] 10.1007/s00429-020-02090-x. [PMID] 32468214.
2020
Deficiency of Meis1, a transcriptional regulator, in mice and worms: Neurochemical and behavioral characterizations with implications in the restless legs syndrome.
Journal of neurochemistry. 155(5):522-537 [DOI] 10.1111/jnc.15177. [PMID] 32910473.
2020
Innovations in Geroscience to enhance mobility in older adults
Experimental Gerontology. [DOI] 10.1016/j.exger.2020.111123. [PMID] 33191210.
2020
Probe the relationship between BTBD9 and MEIS1 in C. elegans and mouse.
Experimental results. 1 [DOI] 10.1017/exp.2020.12. [PMID] 34268480.
2020
Temperature Sensation: From Molecular Thermosensors to Neural Circuits and Coding Principles.
Annual review of physiology. [DOI] 10.1146/annurev-physiol-031220-095215. [PMID] 33085927.
2019
Distinct functions of TMC channels: a comparative overview
Cellular and Molecular Life Sciences. 76(21):4221-4232 [DOI] 10.1007/s00018-019-03214-1.
2018
Brain-gut communications via distinct neuroendocrine signals bidirectionally regulate longevity in C. elegans.
Genes & development. 32(3-4):258-270 [DOI] 10.1101/gad.309625.117. [PMID] 29491136.
2018
Decoding the intensity of sensory input by two glutamate receptors in one C. elegans interneuron
Nature Communications. 9(1) [DOI] 10.1038/s41467-018-06819-5. [PMID] 30333484.
2018
TMC Proteins Modulate Egg Laying and Membrane Excitability through a Background Leak Conductance in C. elegans.
Neuron. 97(3):571-585.e5 [DOI] 10.1016/j.neuron.2017.12.041. [PMID] 29395910.
2017
Membrane ion Channels and Receptors in Animal lifespan Modulation.
Journal of cellular physiology. 232(11):2946-2956 [DOI] 10.1002/jcp.25824. [PMID] 28121014.
2015
Environmental Temperature Differentially Modulates C. elegans Longevity through a Thermosensitive TRP Channel.
Cell reports. 11(9):1414-24 [DOI] 10.1016/j.celrep.2015.04.066. [PMID] 26027928.
2015
RNAi Interrogation of Dietary Modulation of Development, Metabolism, Behavior, and Aging in C. elegans.
Cell reports. 11(7):1123-33 [DOI] 10.1016/j.celrep.2015.04.024. [PMID] 25959815.
2015
Thermosensation and longevity.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. 201(9):857-67 [DOI] 10.1007/s00359-015-1021-8. [PMID] 26101089.
2013
A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel.
Cell. 152(4):806-17 [DOI] 10.1016/j.cell.2013.01.020. [PMID] 23415228.
2011
C. elegans TRP channels.
Advances in experimental medicine and biology. 704:323-39 [DOI] 10.1007/978-94-007-0265-3_18. [PMID] 21290304.
2011
Studying TRP Channels in
TRP Channels. [PMID] 22593955.
2010
Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs.
Pflugers Archiv : European journal of physiology. 459(4):579-92 [DOI] 10.1007/s00424-009-0749-9. [PMID] 19888597.
2010
Mechanosensitive channels: in touch with Piezo.
Current biology : CB. 20(21):R936-8 [DOI] 10.1016/j.cub.2010.09.053. [PMID] 21056836.
2009
Dopamine modulates an mGluR5-mediated depolarization underlying prefrontal persistent activity.
Nature neuroscience. 12(2):190-9 [DOI] 10.1038/nn.2245. [PMID] 19169252.
2009
Function and regulation of TRP family channels in C. elegans.
Pflugers Archiv : European journal of physiology. 458(5):851-60 [DOI] 10.1007/s00424-009-0678-7. [PMID] 19421772.
2009
NAADP mobilizes calcium from acidic organelles through two-pore channels.
Nature. 459(7246):596-600 [DOI] 10.1038/nature08030. [PMID] 19387438.
2008
Calcium plays a central role in the sensitization of TRPV3 channel to repetitive stimulations.
The Journal of biological chemistry. 283(10):6162-74 [DOI] 10.1074/jbc.M706535200. [PMID] 18178557.
2008
Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate.
The Journal of biological chemistry. 283(15):10026-36 [DOI] 10.1074/jbc.M707306200. [PMID] 18230622.
2008
The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active.
Cell calcium. 43(4):334-43 [PMID] 17706768.
2007
The axon-dendrite targeting of Kv3 (Shaw) channels is determined by a targeting motif that associates with the T1 domain and ankyrin G.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(51):14158-70 [PMID] 18094255.
2006
Potentiation of TRPV3 channel function by unsaturated fatty acids.
Journal of cellular physiology. 208(1):201-12 [PMID] 16557504.
2005
Calmodulin and calcium interplay in the modulation of TRPC5 channel activity. Identification of a novel C-terminal domain for calcium/calmodulin-mediated facilitation.
The Journal of biological chemistry. 280(35):30788-96 [PMID] 15987684.
2005
Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes.
Pflugers Archiv : European journal of physiology. 450(5):345-54 [PMID] 15895247.
2004
Mutual dependence of VIP/PACAP and CCK receptor signaling for a physiological role in duck exocrine pancreatic secretion.
American journal of physiology. Regulatory, integrative and comparative physiology. 286(1):R189-98 [PMID] 12947031.
2003
Selective activation by photodynamic action of cholecystokinin receptor in the freshly isolated rat pancreatic acini.
British journal of pharmacology. 139(4):872-80 [PMID] 12813011.

Contact Details

Phones:
Business:
(352) 273-9389
Emails:
Business:
rxiao@ufl.edu
Addresses:
Business Mailing:
PO Box 100274
1345 CENTER DR
GAINESVILLE FL 32610
Business Street:
PO Box 100274
1345 CENTER DR
GAINESVILLE FL 32610